ICD-10-CM FY2026 Code Updates
Computed directly from the official CMS FY2025 and FY2026 code-set releases (effective October 1, 2025).
Compared with FY2025, the FY2026 tabular list in this reference adds 383 new diagnosis code entries, removes 0, and revises the descriptions of 21 existing entries.
Counts reflect tabular-list entries in this reference; CMS's official FY2026 addenda (which also enumerate complete 7th-character code expansions) are the canonical change lists — see the references below.
Largest New Code Families
- L98 — Other disorders of skin and subcutaneous tissue, not elsewhere classified (130 new codes)
- S31 — Open wound of abdomen, lower back, pelvis and external genitals (36 new codes)
- QA0 — Neurodevelopmental disorders related to specific genetic pathogenic variants (20 new codes)
- R10 — Abdominal and pelvic pain (16 new codes)
- T78 — Adverse effects, not elsewhere classified (15 new codes)
- G35 — Multiple sclerosis (10 new codes)
- S30 — Superficial injury of abdomen, lower back, pelvis and external genitals (10 new codes)
- H01 — Other inflammation of eyelid (9 new codes)
- E72 — Other disorders of amino-acid metabolism (8 new codes)
- T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics (8 new codes)
New Codes by Chapter
- Chapter 1: Certain infectious and parasitic diseases (A00-B99) (2 new)
- Chapter 2: Neoplasms (C00-D49) (4 new)
- Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) (3 new)
- Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E89) (25 new)
- Chapter 6: Diseases of the nervous system (G00-G99) (12 new)
- Chapter 7: Diseases of the eye and adnexa (H00-H59) (19 new)
- Chapter 9: Diseases of the circulatory system (I00-I99) (5 new)
- Chapter 12: Diseases of the skin and subcutaneous tissue (L00-L99) (134 new)
- Chapter 13: Diseases of the musculoskeletal system and connective tissue (M00-M99) (1 new)
- Chapter 14: Diseases of the genitourinary system (N00-N99) (7 new)
- Chapter 17: Congenital malformations, deformations and chromosomal abnormalities (Q00-QA0) (31 new)
- Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99) (24 new)
- Chapter 19: Injury, poisoning and certain other consequences of external causes (S00-T88) (77 new)
- Chapter 20: External causes of morbidity (V00-Y99) (11 new)
- Chapter 21: Factors influencing health status and contact with health services (Z00-Z99) (28 new)