E78.5 Hyperlipidemia, unspecified

The ICD-10-CM code for Hyperlipidemia, unspecified is E78.5 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

4: Endocrine, nutritional and metabolic diseases (E00-E89)

Section

E70-E88: Metabolic disorders (E70-E88)

Category E78

24 codes (18 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to E78.5:

• Hyperlipemia, hyperlipidemia
• Dyslipidemia
• Lipoproteinemia
• Hyperlipoproteinemia
• Xanthoma (s), xanthomatosis (primary) (familial) (hereditary) › hyperlipidemic

U.S. Hospital Utilization

• An estimated 8,326,306 U.S. inpatient stays in 2023 included E78.5 among the documented diagnoses.
• 585 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Prevalence & Statistics

• About 86 million US adults age 20 or older have total cholesterol levels above 200 mg/dL, based on 2017-2020 national survey data. (CDC High Cholesterol Facts, 2020)

Official Coding Guidelines

Diabetes mellitus (TOC entry)

a. Diabetes mellitus ................................................................................................................... 39

Obesity (TOC entry)

b. Obesity .................................................................................................................................. 42

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)
• CDC High Cholesterol Facts (2020)