E88.82 Obesity due to disruption of MC4R pathway
The ICD-10-CM code for Obesity due to disruption of MC4R pathway is E88.82 (FY2026). It is a billable, claim-ready diagnosis code.
Classification
- Section
- E70-E88: Metabolic disorders (E70-E88)
- Category E88
- 30 codes (24 billable)
- FY2026 Status
- Introduced in FY2025
Also Known As
ICD-10-CM Alphabetic Index entries that lead to E88.82:
- Obesity › due to › disruption of MC4R pathway
- Obesity › due to › gene mutation › src homology 2B adaptor signaling protein (SH2B1)
- Obesity › due to › gene mutation › proprotein convertase subtilisin/kexin type 1 (PCSK1)
- Obesity › due to › gene mutation › proopiomelanocortin (POMC)
- Obesity › due to › gene mutation › nuclear receptor coactivator 1 (NCOA1)
- Obesity › due to › gene mutation › leptin (LEP)
- Obesity › due to › gene mutation › leptin receptor (LEPR)
- Obesity › due to › gene mutation › melanocortin 4 Receptor (MC4R)
Official Coding Guidelines
E66 obesity codes include causes/effects; other obesity codes existb. Obesity The obesity codes in category E66, Overweight and obesity, include codes related to the cause of obesity, such as drug-induced obesity (E66.1), and codes related to effects of obesity, such as code E66.2, Morbid (severe) obesity with alveolar hypoventilation. There are other codes related to obesity in other categories of the classification, such as E88.82, Obesity due to disruption of MC4R pathway; and codes in fifth character subcategory O99.21, Obesity complicating pregnancy, childbirth, and the puerperium.
Diabetes mellitus (TOC entry)a. Diabetes mellitus ................................................................................................................... 39
Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026