E85.4 Organ-limited amyloidosis

The ICD-10-CM code for Organ-limited amyloidosis is E85.4 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

4: Endocrine, nutritional and metabolic diseases (E00-E89)

Section

E70-E88: Metabolic disorders (E70-E88)

Category E85

11 codes (9 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to E85.4:

• Amyloid heart (disease)
• Amyloidosis (generalized) (primary) › heart
• Amyloidosis (generalized) (primary) › skin (lichen) (macular)
• Amyloidosis (generalized) (primary) › pulmonary
• Amyloidosis (generalized) (primary) › organ limited
• Amyloidosis (generalized) (primary) › localized
• Amyloidosis (generalized) (primary) › liver
• Amyloidosis (generalized) (primary) › subglottic

Inclusion Terms

• Localized amyloidosis
• Transthyretin-related (ATTR) familial amyloid cardiomyopathy

U.S. Hospital Utilization

• An estimated 38,055 U.S. inpatient stays in 2023 included E85.4 among the documented diagnoses.
• 3,490 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Diabetes mellitus (TOC entry)

a. Diabetes mellitus ................................................................................................................... 39

Obesity (TOC entry)

b. Obesity .................................................................................................................................. 42

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)

Cite This Page

Reference E85.4 with the canonical source and edition:

E85.4 — Organ-limited amyloidosis. ICD-10 Coding Pro (ICD-10-CM FY2026). https://icd10codingpro.com/codes/E85.4

Canonical URL: https://icd10codingpro.com/codes/E85.4