E85.1 Neuropathic heredofamilial amyloidosis

The ICD-10-CM code for Neuropathic heredofamilial amyloidosis is E85.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

4: Endocrine, nutritional and metabolic diseases (E00-E89)

Section

E70-E88: Metabolic disorders (E70-E88)

Category E85

11 codes (9 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to E85.1:

• Amyloidosis (generalized) (primary) › Portuguese
• Amyloidosis (generalized) (primary) › neuropathic heredofamilial
• Polyneuropathy (peripheral) › amyloid (Portuguese)
• Polyneuropathy (peripheral) › in (due to) › amyloidosis, familial (Portuguese)
• Polyneuropathy (peripheral) › in (due to) › transthyretin-related (ATTR) familial amyloid
• Polyneuropathy (peripheral) › amyloid (Portuguese) › transthyretin-related (ATTR) familial

Inclusion Terms

• Amyloid polyneuropathy (Portuguese)
• Transthyretin-related (ATTR) familial amyloid polyneuropathy

U.S. Hospital Utilization

• An estimated 260 U.S. inpatient stays in 2023 included E85.1 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Diabetes mellitus (TOC entry)

a. Diabetes mellitus ................................................................................................................... 39

Obesity (TOC entry)

b. Obesity .................................................................................................................................. 42

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)