D68.5 Primary thrombophilia

⚠ Non-Billable ICD-10-CM 2026
Open D68.5 in Web App →

The ICD-10-CM code for Primary thrombophilia is D68.5 (FY2026). It is a non-billable category code — select a more specific code below for claims.

Classification

Section
D65-D69: Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)
Category D68
32 codes (25 billable)
FY2026 Status
Stable since FY2024
Excludes1
Not coded here. These conditions should NOT be coded together with D68.5.
  • antiphospholipid syndrome (D68.61)
  • lupus anticoagulant (D68.62)
  • secondary activated protein C resistance (D68.69)
  • secondary antiphospholipid antibody syndrome (D68.69)
  • secondary lupus anticoagulant with hypercoagulable state (D68.69)
  • secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69)
  • systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
  • systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312)
  • thrombotic thrombocytopenic purpura (M31.19)

Inclusion Terms

  • Primary hypercoagulable states

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3
Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3.Reserved

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

Parent Code

D68 Other coagulation defects

More Specific Codes

D68.51 Activated protein C resistance D68.52 Prothrombin gene mutation D68.59 Other primary thrombophilia

Related Codes in D68

D68 Other coagulation defects D68.0 Von Willebrand disease D68.00 Von Willebrand disease, unspecified D68.01 Von Willebrand disease, type 1 D68.02 Von Willebrand disease, type 2 D68.020 Von Willebrand disease, type 2A D68.021 Von Willebrand disease, type 2B D68.022 Von Willebrand disease, type 2M D68.023 Von Willebrand disease, type 2N D68.029 Von Willebrand disease, type 2, unspecified D68.03 Von Willebrand disease, type 3 D68.04 Acquired von Willebrand disease D68.09 Other von Willebrand disease D68.1 Hereditary factor XI deficiency D68.2 Hereditary deficiency of other clotting factors D68.3 Hemorrhagic disorder due to circulating anticoagulants D68.31 Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors D68.311 Acquired hemophilia D68.312 Antiphospholipid antibody with hemorrhagic disorder D68.318 Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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