D68.021 Von Willebrand disease, type 2B

The ICD-10-CM code for Von Willebrand disease, type 2B is D68.021 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Section

D65-D69: Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)

Category D68

32 codes (25 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to D68.021:

• Defect, defective › qualitative, of von Willebrand factor › with › high-molecular-weight von Willebrand factor loss
• Defect, defective › qualitative, of von Willebrand factor › with › hyper-adhesive forms
• Defect, defective › qualitative, of von Willebrand factor › with › increased affinity for platelet glycoprotein lb
• Disease, diseased › von Willebrand (-Jürgens) (angiohemophilia) › type 2 › type 2B

Inclusion Terms

• Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss
• Qualitative defects of von Willebrand factor with hyper-adhesive forms
• Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb

U.S. Hospital Utilization

• An estimated 310 U.S. inpatient stays in 2023 included D68.021 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)

Cite This Page

Reference D68.021 with the canonical source and edition:

D68.021 — Von Willebrand disease, type 2B. ICD-10 Coding Pro (ICD-10-CM FY2026). https://icd10codingpro.com/codes/D68.021

Canonical URL: https://icd10codingpro.com/codes/D68.021