D68.1 Hereditary factor XI deficiency

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Hereditary factor XI deficiency is D68.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
D65-D69: Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)
Category D68
32 codes (25 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to D68.1:

  • Rosenthal's disease or syndrome
  • Disease, diseased › Rosenthal's (factor XI deficiency)
  • Hemophilia (classical) (familial) (hereditary) › C
  • Deficiency, deficient › PTA (plasma thromboplastin antecedent)
  • Deficiency, deficient › plasma thromboplastin › antecedent (PTA)
  • Deficiency, deficient › factor › XI (congenital) (hereditary)
  • Deficiency, deficient › anti-hemophilic › factor (A) › C

Inclusion Terms

  • Hemophilia C
  • Plasma thromboplastin antecedent [PTA] deficiency
  • Rosenthal's disease

U.S. Hospital Utilization

  • An estimated 2,030 U.S. inpatient stays in 2023 included D68.1 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3
Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3.Reserved

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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