D56.3 Thalassemia minor

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Thalassemia minor is D56.3 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
D55-D59: Hemolytic anemias (D55-D59)
Category D56
9 codes (8 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to D56.3:

  • Trait (s) › Lepore
  • Thalassemia (anemia) (disease) › minor
  • Thalassemia (anemia) (disease) › trait
  • Thalassemia (anemia) (disease) › beta (severe) › minor
  • Thalassemia (anemia) (disease) › alpha (major) (severe) (triple gene defect) › silent carrier
  • Thalassemia (anemia) (disease) › beta (severe) › trait
  • Thalassemia (anemia) (disease) › alpha (major) (severe) (triple gene defect) › minor
  • Thalassemia (anemia) (disease) › alpha (major) (severe) (triple gene defect) › trait
Excludes1
Not coded here. These conditions should NOT be coded together with D56.3.
  • alpha thalassemia (D56.0)
  • beta thalassemia (D56.1)
  • delta-beta thalassemia (D56.2)
  • hemoglobin E-beta thalassemia (D56.5)
  • sickle-cell trait (D57.3)

Inclusion Terms

  • Alpha thalassemia minor
  • Alpha thalassemia silent carrier
  • Alpha thalassemia trait
  • Beta thalassemia minor
  • Beta thalassemia trait
  • Delta-beta thalassemia minor
  • Delta-beta thalassemia trait
  • Thalassemia trait NOS

U.S. Hospital Utilization

  • An estimated 32,065 U.S. inpatient stays in 2023 included D56.3 among the documented diagnoses.
  • 100 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3
Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3.Reserved

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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