ICD-10 Code for hypoglycemia

The ICD-10-CM code for hypoglycemia is E16.2 when documented without further specification. Hypoglycemia codes in category E16. E16.2 is unspecified (non-diabetic) hypoglycemia. Per its Excludes1, a diabetic's hypoglycemia is coded to the diabetes-with-hypoglycemia combination codes (E08.649-E13.649), not E16.2. Use an additional code for the hypoglycemia level (E16.A-) when documented.

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Symptom code vs. confirmed diagnosis

E16.2 is a confirmed-diagnosis code for documented non-diabetic hypoglycemia, not a bare low-glucose reading. Per the Excludes1, when the patient has diabetes the hypoglycemia is coded with the diabetes-with-hypoglycemia code (e.g., E11.649), not E16.2.

Which Code Should You Use?

E16.2 ✓ Billable — Hypoglycemia, unspecified

Hypoglycemia, unspecified (non-diabetic), with no cause or level specified.

E16.0 ✓ Billable — Drug-induced hypoglycemia without coma

Drug-induced hypoglycemia without coma.

E16.1 ✓ Billable — Other hypoglycemia

Other (specified non-diabetic) hypoglycemia.

E11.649 ✓ Billable — Type 2 diabetes mellitus with hypoglycemia without coma

Type 2 diabetes mellitus with hypoglycemia without coma - a diabetic's hypoglycemia is coded here, not E16.2 (Excludes1).

What to Document

  • Whether the patient has diabetes, since per the Excludes1 a diabetic's hypoglycemia is coded to E08.649/E10.649/E11.649/E13.649, not E16.2.
  • The hypoglycemia level when documented - E16.2 carries a use-additional-code instruction for the level (E16.A1, E16.A2, or E16.A3).
  • Whether the hypoglycemia is drug-induced (E16.0) or another specified type (E16.1).

Common Documentation Pitfalls

  • Per the Excludes1, do not assign E16.2 for a diabetic patient's hypoglycemia - use the diabetes-with-hypoglycemia combination code (e.g., E11.649).
  • Per the use-additional-code note, report the hypoglycemia level (E16.A-) in addition when the provider documents it.
  • Drug-induced hypoglycemia is E16.0, distinct from the unspecified E16.2.

Instructional Notes for E16.2

Excludes1
Not coded here. These conditions should NOT be coded together with E16.2.
  • diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649)
Use Additional Code
  • code for hypoglycemia level, if applicable (E16.A-)

Also Known As

Official ICD-10-CM Alphabetic Index terms that point to E16.2:

  • McQuarrie's syndrome (idiopathic familial hypoglycemia)
  • Glycopenia
  • Hypoglycemia (spontaneous)
  • Syndrome › McQuarrie's
  • Decrease (d) › glucose
  • Syndrome › hypoglycemic (familial) (neonatal)
  • Encephalopathy (acute) › hypoglycemic
  • Decrease (d) › blood › glucose

Coding Notes

E16.2 is unspecified non-diabetic hypoglycemia. Its Excludes1 sends a diabetic's hypoglycemia to the diabetes combination codes (E08.649, E10.649, E11.649, E13.649). A use-additional-code note directs reporting the hypoglycemia level (E16.A1-E16.A3) when documented.

References

Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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