E16.1 Other hypoglycemia

The ICD-10-CM code for Other hypoglycemia is E16.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

4: Endocrine, nutritional and metabolic diseases (E00-E89)

Section

E15-E16: Other disorders of glucose regulation and pancreatic internal secretion (E15-E16)

Category E16

12 codes (10 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to E16.1:

• Hyperinsulinism (functional)
• Encephalopathy (acute) › posthypoglycemic (coma)
• Hypoglycemia (spontaneous) › functional, nonhyperinsulinemic
• Hypoglycemia (spontaneous) › infantile
• Hypoglycemia (spontaneous) › reactive (not drug-induced)
• Hyperinsulinism (functional) › ectopic
• Encephalopathy (acute) › in (due to) (with) › hyperinsulinism
• Hyperinsulinism (functional) › with › encephalopathy

Inclusion Terms

• Functional hyperinsulinism
• Functional nonhyperinsulinemic hypoglycemia
• Hyperinsulinism NOS
• Hyperplasia of pancreatic islet beta cells NOS

U.S. Hospital Utilization

• An estimated 6,915 U.S. inpatient stays in 2023 included E16.1 among the documented diagnoses.
• 1,900 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Diabetes mellitus (TOC entry)

a. Diabetes mellitus ................................................................................................................... 39

Obesity (TOC entry)

b. Obesity .................................................................................................................................. 42

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)