U0005 Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc, making use of high throughput technologies, completed within 2 calendar days from date of specimen collection (list separately in addition to either hcpcs code u0003 or u0004) as described by cms-2020-01-r2

Short descriptor: Infec agen detec ampli probe

⚠ Terminated HCPCS Level II 2026
Terminated Code
U0005 was terminated as of 2023-05-11 and should not be reported for dates of service after that date. This page is retained for historical reference.
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U0005 is the HCPCS Level II code for Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc, making use of high throughput technologies, completed within 2 calendar days from date of specimen collection (list separately in addition to either hcpcs code u0003 or u0004) as described by cms-2020-01-r2 (2026). It belongs to Section U — Coronavirus Laboratory Tests. Under Medicare, its coverage status is: Carrier judgment. Part B pricing methodology: Priced by carriers (clinical lab).

Classification & CMS Attributes

Medicare Coverage
Carrier judgment (code C)
Part B Pricing
Priced by carriers (clinical lab) (indicator 22)
Type of Service
Diagnostic laboratory
Effective Date
2023-05-12
Termination Date
2023-05-11
2026 Maintenance
No change this year

References

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Reference U0005 with the canonical source and edition:

U0005 — Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc, making use of high throughput technologies, completed within 2 calendar days from date of specimen collection (list separately in addition to either hcpcs code u0003 or u0004) as described by cms-2020-01-r2. ICD-10 Coding Pro (HCPCS Level II 2026). https://icd10codingpro.com/hcpcs-codes/U0005

Canonical URL: https://icd10codingpro.com/hcpcs-codes/U0005

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2026-01-01

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