C5278 Application of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure)

Short descriptor: Low cost skin substitute app

⚠ Terminated HCPCS Level II 2026
Terminated Code
C5278 was terminated as of 2025-12-31 and should not be reported for dates of service after that date. This page is retained for historical reference.
Open C5278 in the app →

Look up C5278 alongside ICD-10-CM diagnoses, the HCPCS Table of Drugs, and the AI coding assistant.

C5278 is the HCPCS Level II code for Application of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure) (2026). It belongs to Section C — Outpatient PPS (Hospital). Under Medicare, its coverage status is: Special coverage instructions apply. Part B pricing methodology: Statute.

Classification & CMS Attributes

Medicare Coverage
Special coverage instructions apply (code D)
Part B Pricing
Statute (indicator 53)
Type of Service
Surgery
Effective Date
2026-01-01
Termination Date
2025-12-31
2026 Maintenance
Discontinued

References

Cite This Page

Reference C5278 with the canonical source and edition:

C5278 — Application of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure). ICD-10 Coding Pro (HCPCS Level II 2026). https://icd10codingpro.com/hcpcs-codes/C5278

Canonical URL: https://icd10codingpro.com/hcpcs-codes/C5278

Related Codes in Section C

Browse all HCPCS Level II sections →
Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2026-01-01

Get HCC Mappings, Clinical Summaries, and More

Access premium features including HCC risk adjustment, FDA drug indications, AI coding assistant, and comprehensive clinical context.

Start Free Trial