Z16.10 Resistance to unspecified beta lactam antibiotics
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The ICD-10-CM code for Resistance to unspecified beta lactam antibiotics is Z16.10 (FY2026). It is a billable, claim-ready diagnosis code.
Classification
- Section
- Z16: Resistance to antimicrobial drugs (Z16)
- Category Z16
- 24 codes (19 billable)
- FY2026 Status
- Stable since FY2024
Also Known As
ICD-10-CM Alphabetic Index entries that lead to Z16.10:
- Resistance, resistant (to) › organism (s) › to › drug › beta lactam antibiotics
U.S. Hospital Utilization
- An estimated 550 U.S. inpatient stays in 2023 included Z16.10 among the documented diagnoses.
Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.
Official Coding Guidelines
Used with any code in range A00.0-T88.9, Z00-Z991) Used with any code in the range of A00.0-T88.9, Z00-Z99 An external cause code may be used with any code in the range of A00.0-T88.9, Z00-Z99, classification that represents a health condition due to an external cause. Though they are most applicable to injuries, they are also valid for use with such things as infections or diseases due to an external source, and other health conditions, such as a heart attack that occurs during strenuous physical activity.
Additional codes with observation code (fragment)observation code, but only if they are unrelated to the suspected condition being observed.
Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026
References
Cite This Page
Reference Z16.10 with the canonical source and edition:
Z16.10 — Resistance to unspecified beta lactam antibiotics. ICD-10 Coding Pro (ICD-10-CM FY2026). https://icd10codingpro.com/codes/Z16.10
Canonical URL: https://icd10codingpro.com/codes/Z16.10