Z00.6 Encounter for examination for normal comparison and control in clinical research program

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Encounter for examination for normal comparison and control in clinical research program is Z00.6 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
Z00-Z13: Persons encountering health services for examinations (Z00-Z13)
Category Z00
19 codes (13 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to Z00.6:

  • Clinical research investigation (clinical trial) (control subject) (normal comparison) (participant)
  • Person (with) › admitted for clinical research, as a control subject (normal comparison) (participant)
  • Examination (for) (following) (general) (of) (routine) › clinical research control or normal comparison (control) (participant)
  • Admission (for) › clinical research investigation (control) (normal comparison) (participant)
  • Investigation › clinical research subject (control) (normal comparison) (participant)
  • Admission (for) › examination at health care facility (adult) › clinical research investigation (control) (normal comparison) (participant)
  • Examination (for) (following) (general) (of) (routine) › medical (adult) (for) (of) › clinical research, normal subject (control) (participant)
  • Examination (for) (following) (general) (of) (routine) › medical (adult) (for) (of) › control subject in clinical research (normal comparison) (participant)

Inclusion Terms

  • Examination of participant or control in clinical research program

U.S. Hospital Utilization

  • An estimated 252,080 U.S. inpatient stays in 2023 included Z00.6 among the documented diagnoses.
  • 235 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Z codes restricted to principal/first-listed (with exception)

15) Z Codes That May Only be Principal/First-Listed Diagnosis The following Z codes/subcategories/categories may only be reported as the principal/first-listed diagnosis, except when there are multiple encounters on the same day and the medical records for the encounters are combined: Z00 Encounter for general examination without complaint, suspected or reported diagnosis Except: Z00.6 Z01 Encounter for other special examination without complaint, suspected or reported diagnosis Z02 Encounter for administrative examination Z04 Encounter for examination and observation for other reasons Z33.2 Encounter for elective termination of pregnancy

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.21.15
Used with any code in range A00.0-T88.9, Z00-Z99

1) Used with any code in the range of A00.0-T88.9, Z00-Z99 An external cause code may be used with any code in the range of A00.0-T88.9, Z00-Z99, classification that represents a health condition due to an external cause. Though they are most applicable to injuries, they are also valid for use with such things as infections or diseases due to an external source, and other health conditions, such as a heart attack that occurs during strenuous physical activity.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.20.a.1

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Cite This Page

Reference Z00.6 with the canonical source and edition:

Z00.6 — Encounter for examination for normal comparison and control in clinical research program. ICD-10 Coding Pro (ICD-10-CM FY2026). https://icd10codingpro.com/codes/Z00.6

Canonical URL: https://icd10codingpro.com/codes/Z00.6

Related Codes

Parent Code

Z00 Encounter for general examination without complaint, suspected or reported diagnosis

Related Codes in Z00

Z00 Encounter for general examination without complaint, suspected or reported diagnosis Z00.0 Encounter for general adult medical examination Z00.00 Encounter for general adult medical examination without abnormal findings Z00.01 Encounter for general adult medical examination with abnormal findings Z00.1 Encounter for newborn, infant and child health examinations Z00.11 Newborn health examination Z00.110 Health examination for newborn under 8 days old Z00.111 Health examination for newborn 8 to 28 days old Z00.12 Encounter for routine child health examination Z00.121 Encounter for routine child health examination with abnormal findings Z00.129 Encounter for routine child health examination without abnormal findings Z00.2 Encounter for examination for period of rapid growth in childhood Z00.3 Encounter for examination for adolescent development state Z00.5 Encounter for examination of potential donor of organ and tissue Z00.7 Encounter for examination for period of delayed growth in childhood Z00.70 Encounter for examination for period of delayed growth in childhood without abnormal findings Z00.71 Encounter for examination for period of delayed growth in childhood with abnormal findings Z00.8 Encounter for other general examination
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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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