T65 Toxic effect of other and unspecified substances

⚠ Non-Billable ICD-10-CM 2026
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The ICD-10-CM code for Toxic effect of other and unspecified substances is T65 (FY2026). It is a non-billable category code — select a more specific code below for claims.

Classification

Section
T51-T65: Toxic effects of substances chiefly nonmedicinal as to source (T51-T65)
Category T65
84 codes (60 billable)
FY2026 Status
Stable since FY2024

Official Coding Guidelines

T36-T65 are combination codes; no additional external cause code

e. Adverse Effects, Poisoning, Underdosing and Toxic Effects Codes in categories T36-T65 are combination codes that include the substance that was taken as well as the intent. No additional external cause code is required for poisonings, toxic effects, adverse effects and underdosing codes.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.19.e
Toxic effects: code T51-T65 first, then manifestations

(d) Toxic Effects When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65. When coding a toxic effect, assign the toxic effect code first, followed by codes for all associated manifestations of the toxic effect.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.19.e.(d)

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

More Specific Codes

T65.0 Toxic effect of cyanides T65.0X Toxic effect of cyanides T65.0X1 Toxic effect of cyanides, accidental (unintentional) T65.0X2 Toxic effect of cyanides, intentional self-harm T65.0X3 Toxic effect of cyanides, assault T65.0X4 Toxic effect of cyanides, undetermined T65.1 Toxic effect of strychnine and its salts T65.1X Toxic effect of strychnine and its salts T65.1X1 Toxic effect of strychnine and its salts, accidental (unintentional) T65.1X2 Toxic effect of strychnine and its salts, intentional self-harm T65.1X3 Toxic effect of strychnine and its salts, assault T65.1X4 Toxic effect of strychnine and its salts, undetermined T65.2 Toxic effect of tobacco and nicotine T65.21 Toxic effect of chewing tobacco T65.211 Toxic effect of chewing tobacco, accidental (unintentional) T65.212 Toxic effect of chewing tobacco, intentional self-harm T65.213 Toxic effect of chewing tobacco, assault T65.214 Toxic effect of chewing tobacco, undetermined T65.22 Toxic effect of tobacco cigarettes T65.221 Toxic effect of tobacco cigarettes, accidental (unintentional) T65.222 Toxic effect of tobacco cigarettes, intentional self-harm T65.223 Toxic effect of tobacco cigarettes, assault T65.224 Toxic effect of tobacco cigarettes, undetermined T65.29 Toxic effect of other tobacco and nicotine T65.291 Toxic effect of other tobacco and nicotine, accidental (unintentional) T65.292 Toxic effect of other tobacco and nicotine, intentional self-harm T65.293 Toxic effect of other tobacco and nicotine, assault T65.294 Toxic effect of other tobacco and nicotine, undetermined T65.3 Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues T65.3X Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues

Related Codes in T65

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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