P04.49 Newborn affected by maternal use of other drugs of addiction

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Newborn affected by maternal use of other drugs of addiction is P04.49 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
P00-P04: Newborn affected by maternal factors and by complications of pregnancy, labor, and delivery (P00-P04)
Category P04
26 codes (22 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to P04.49:

  • Newborn (infant) (liveborn) (singleton) › affected by › methamphetamine (s)
  • Newborn (infant) (liveborn) (singleton) › affected by › drugs of addiction › specified drug NEC
  • Newborn (infant) (liveborn) (singleton) › affected by › maternal (complication of) (use of) › drugs (addictive) (illegal) NEC
  • Absorption › drug NEC › addictive › through placenta (newborn) › specified drug NEC
Excludes2
Not included here. These conditions are coded elsewhere but may be coded together if applicable.
  • newborn affected by maternal anesthesia and analgesia (P04.0)
  • withdrawal symptoms from maternal use of drugs of addiction (P96.1)

U.S. Hospital Utilization

  • An estimated 17,690 U.S. inpatient stays in 2023 included P04.49 among the documented diagnoses.
  • 95 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Use of Z05 codes (newborn suspected condition ruled out)

1) Use of Z05 codes Assign a code from category Z05, Observation and evaluation of newborn for suspected diseases and conditions ruled out, to identify those instances when a healthy newborn is evaluated for a suspected condition/disease that is determined after study not to be present. Do not use a code from category Z05 when the patient is documented to have signs or symptoms of a suspected problem; in such cases code the sign or symptom.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.16.b.1
Z05 on other than the birth record

2) Z05 on other than the birth record A code from category Z05 may also be assigned as a principal or first- listed code for readmissions or encounters when the code from category Z38 code no longer applies. Codes from category Z05 are for use only for healthy newborns and infants for which no condition after study is found to be present.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.16.b.2

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

Parent Code

P04 Newborn affected by noxious substances transmitted via placenta or breast milk

Related Codes in P04

P04 Newborn affected by noxious substances transmitted via placenta or breast milk P04.0 Newborn affected by maternal anesthesia and analgesia in pregnancy, labor and delivery P04.1 Newborn affected by other maternal medication P04.11 Newborn affected by maternal antineoplastic chemotherapy P04.12 Newborn affected by maternal cytotoxic drugs P04.13 Newborn affected by maternal use of anticonvulsants P04.14 Newborn affected by maternal use of opiates P04.15 Newborn affected by maternal use of antidepressants P04.16 Newborn affected by maternal use of amphetamines P04.17 Newborn affected by maternal use of sedative-hypnotics P04.18 Newborn affected by other maternal medication P04.19 Newborn affected by maternal use of unspecified medication P04.1A Newborn affected by maternal use of anxiolytics P04.2 Newborn affected by maternal use of tobacco P04.3 Newborn affected by maternal use of alcohol P04.4 Newborn affected by maternal use of drugs of addiction P04.40 Newborn affected by maternal use of unspecified drugs of addiction P04.41 Newborn affected by maternal use of cocaine P04.42 Newborn affected by maternal use of hallucinogens P04.5 Newborn affected by maternal use of nutritional chemical substances
Search all 70,000+ ICD-10-CM codes →
Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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