N16 Renal tubulo-interstitial disorders in diseases classified elsewhere

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Renal tubulo-interstitial disorders in diseases classified elsewhere is N16 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
N10-N16: Renal tubulo-interstitial diseases (N10-N16)
Category N16
1 code (1 billable)
FY2026 Status
Stable since FY2024
Excludes1
Not coded here. These conditions should NOT be coded together with N16.
  • diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
  • pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
  • pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
  • pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
  • pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
  • pyelonephritis and tubulo-interstitial nephritis in Sjogren syndrome (M35.04)
  • pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
  • pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
  • renal tubular degeneration in diabetes (E08-E13 with .29)
  • syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)
Code First
  • underlying disease, such as:
  • brucellosis (A23.0-A23.9)
  • cryoglobulinemia (D89.1)
  • glycogen storage disease (E74.0-)
  • leukemia (C91-C95)
  • lymphoma (C81.0-C85.9, C96.0-C96.9)
  • multiple myeloma (C90.0-)
  • sepsis (A40.0-A41.9)
  • Wilson's disease (E83.01)

Inclusion Terms

  • Pyelonephritis
  • Tubulo-interstitial nephritis

U.S. Hospital Utilization

  • An estimated 6,115 U.S. inpatient stays in 2023 included N16 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

CKD staging and code assignment (N18.-)

The ICD-10-CM classifies CKD based on severity. The severity of CKD is designated by stages 1-5. Stage 2, code N18.2, equates to mild CKD; stage 3, codes N18.30-N18.32, equate to moderate CKD; and stage 4, code N18.4, equates to severe CKD. Code N18.6, End stage renal disease (ESRD), is assigned when the provider has documented end- stage renal disease (ESRD).

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.14.a.1
CKD stage plus ESRD: assign N18.6 only

If both a stage of CKD and ESRD are documented, assign code N18.6 only.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.14.a.1

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Search all 70,000+ ICD-10-CM codes →
Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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