I21 Acute myocardial infarction

The ICD-10-CM code for Acute myocardial infarction is I21 (FY2026). It is a non-billable category code — select a more specific code below for claims.

Classification

Chapter

9: Diseases of the circulatory system (I00-I99)

Section

I20-I25: Ischemic heart diseases (I20-I25)

Category I21

18 codes (13 billable)

FY2026 Status

Stable since FY2024

Official Coding Guidelines

Report I21 within 4 weeks; aftercare after; I25.2 for old/healed

For encounters occurring while the myocardial infarction is equal to, or less than, four weeks old, including transfers to another acute setting or a postacute setting, and the myocardial infarction meets the definition for “other diagnoses” (see Section III, Reporting Additional Diagnoses), codes from category I21 may continue to be reported. For encounters after the 4-week time frame and the patient is still receiving care related to the myocardial infarction, the appropriate aftercare code should be assigned, rather than a code from category I21. For old or healed myocardial infarctions not requiring further care, code I25.2, Old myocardial infarction, may be assigned.

Use of I22 for subsequent AMI within 4 weeks; with I21

4) Subsequent acute myocardial infarction A code from category I22, Subsequent ST elevation (STEMI) and non- ST elevation (NSTEMI) myocardial infarction, is to be used when a patient who has suffered a type 1 or unspecified AMI has a new AMI within the 4 week time frame of the initial AMI. A code from category I22 must be used in conjunction with a code from category I21. The sequencing of the I22 and I21 codes depends on the circumstances of the encounter.

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool