E34.322 Insulin-like growth factor-1 (IGF-1) resistance

✓ Billable ICD-10-CM 2026
Open E34.322 in Web App →

The ICD-10-CM code for Insulin-like growth factor-1 (IGF-1) resistance is E34.322 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
E20-E35: Disorders of other endocrine glands (E20-E35)
Category E34
23 codes (18 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to E34.322:

  • Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › insulin-like growth factor-1 receptor (IGF-1R) defect
  • Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › genetic syndrome with resistance to insulin-like growth factor-1
  • Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › insulin-like growth factor-1 (IGF-1) resistance
  • Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › post-insulin-like growth factor-1 receptor signaling defect

Inclusion Terms

  • Genetic syndrome with resistance to insulin-like growth factor-1
  • Insulin-like growth factor-1 receptor (IGF-1R) defect
  • Post-insulin-like growth factor-1 receptor signaling defect

U.S. Hospital Utilization

E34.322 appeared in too few sampled U.S. inpatient stays in 2023 to report a national estimate (AHRQ suppresses counts of 10 or fewer) — a rare inpatient diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Diabetes mellitus (TOC entry)

a. Diabetes mellitus ................................................................................................................... 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.4.a
Obesity (TOC entry)

b. Obesity .................................................................................................................................. 42

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.4.b

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

Parent Code

E34 Other endocrine disorders

Related Codes in E34

E34 Other endocrine disorders E34.0 Carcinoid syndrome E34.00 Carcinoid syndrome, unspecified E34.01 Carcinoid heart syndrome E34.09 Other carcinoid syndrome E34.1 Other hypersecretion of intestinal hormones E34.2 Ectopic hormone secretion, not elsewhere classified E34.3 Short stature due to endocrine disorder E34.30 Short stature due to endocrine disorder, unspecified E34.31 Constitutional short stature E34.32 Genetic causes of short stature E34.321 Primary insulin-like growth factor-1 (IGF-1) deficiency E34.328 Other genetic causes of short stature E34.329 Unspecified genetic causes of short stature E34.39 Other short stature due to endocrine disorder E34.4 Constitutional tall stature E34.5 Androgen insensitivity syndrome E34.50 Androgen insensitivity syndrome, unspecified E34.51 Complete androgen insensitivity syndrome E34.52 Partial androgen insensitivity syndrome
Search all 70,000+ ICD-10-CM codes →
Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

Get HCC Mappings, Clinical Summaries, and More

Access premium features including HCC risk adjustment, FDA drug indications, AI coding assistant, and comprehensive clinical context.

Start Free Trial