D80.1 Nonfamilial hypogammaglobulinemia

The ICD-10-CM code for Nonfamilial hypogammaglobulinemia is D80.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Section

D80-D89: Certain disorders involving the immune mechanism (D80-D89)

Category D80

11 codes (10 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to D80.1:

• Hypogammaglobulinemia
• Agammaglobulinemia (acquired (secondary)) (nonfamilial)
• Agammaglobulinemia (acquired (secondary)) (nonfamilial) › common variable (CVAgamma)
• Hypogammaglobulinemia › nonfamilial
• Deficiency, deficient › gammaglobulin in blood
• Absence (of) (organ or part) (complete or partial) › gamma globulin in blood
• Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) › in (due to) › hypogammaglobulinemia
• Agammaglobulinemia (acquired (secondary)) (nonfamilial) › with › immunoglobulin-bearing B-lymphocytes

Inclusion Terms

• Agammaglobulinemia with immunoglobulin-bearing B-lymphocytes
• Common variable agammaglobulinemia [CVAgamma]
• Hypogammaglobulinemia NOS

U.S. Hospital Utilization

• An estimated 33,035 U.S. inpatient stays in 2023 included D80.1 among the documented diagnoses.
• 95 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)

Cite This Page

Reference D80.1 with the canonical source and edition:

D80.1 — Nonfamilial hypogammaglobulinemia. ICD-10 Coding Pro (ICD-10-CM FY2026). https://icd10codingpro.com/codes/D80.1

Canonical URL: https://icd10codingpro.com/codes/D80.1