D57.433 Sickle-cell thalassemia beta zero with cerebral vascular involvement

The ICD-10-CM code for Sickle-cell thalassemia beta zero with cerebral vascular involvement is D57.433 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Section

D55-D59: Hemolytic anemias (D55-D59)

Category D57

53 codes (43 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to D57.433:

• Disease, diseased › hemoglobin or Hb › S or SS › beta zero › with › cerebral vascular involvement
• Disease, diseased › sickle-cell › thalassemia › beta zero › with › cerebral vascular involvement

Inclusion Terms

• HbS-beta zero with cerebral vascular involvement
• Sickle-cell beta zero with cerebral vascular involvement

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool