A51.5 Early syphilis, latent

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Early syphilis, latent is A51.5 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
A50-A64: Infections with a predominantly sexual mode of transmission (A50-A64)
Category A51
18 codes (15 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to A51.5:

  • Syphilis, syphilitic (acquired) › latent › early, or less than 2 years after infection
  • Syphilis, syphilitic (acquired) › early › latent (without manifestations) (less than 2 years after infection)
  • Syphilis, syphilitic (acquired) › early › latent (without manifestations) (less than 2 years after infection) › negative spinal fluid test
  • Syphilis, syphilitic (acquired) › latent › positive serology (only finding) › early, or less than 2 years after infection
  • Syphilis, syphilitic (acquired) › early › latent (without manifestations) (less than 2 years after infection) › serology positive
  • Syphilis, syphilitic (acquired) › early › latent (without manifestations) (less than 2 years after infection) › serological relapse after treatment

Inclusion Terms

  • Syphilis (acquired) without clinical manifestations, with positive serological reaction and negative spinal fluid test, less than two years after infection.

U.S. Hospital Utilization

  • An estimated 365 U.S. inpatient stays in 2023 included A51.5 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

HIV Infections (TOC entry)

a. Human Immunodeficiency Virus (HIV) Infections .............................................................. 19

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.1.a
Infectious agents causing diseases in other chapters (TOC)

b. Infectious agents as the cause of diseases classified to other chapters ................................. 22

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.1.b

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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