Z79.81 Long term (current) use of agents affecting estrogen receptors and estrogen levels

⚠ Non-Billable ICD-10-CM 2026
Open Z79.81 in Web App →

The ICD-10-CM code for Long term (current) use of agents affecting estrogen receptors and estrogen levels is Z79.81 (FY2026). It is a non-billable category code — select a more specific code below for claims.

Classification

Section
Z77-Z99: Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99)
Category Z79
41 codes (32 billable)
FY2026 Status
Stable since FY2024
Excludes1
Not coded here. These conditions should NOT be coded together with Z79.81.
  • hormone replacement therapy (Z79.890)
Code First
  • , if applicable:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of prostate (C61)
Use Additional Code
  • code, if applicable, to identify:
  • estrogen receptor positive status (Z17.0)
  • family history of breast cancer (Z80.3)
  • genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
  • personal history of breast cancer (Z85.3)
  • personal history of prostate cancer (Z85.46)
  • postmenopausal status (Z78.0)

Official Coding Guidelines

Used with any code in range A00.0-T88.9, Z00-Z99

1) Used with any code in the range of A00.0-T88.9, Z00-Z99 An external cause code may be used with any code in the range of A00.0-T88.9, Z00-Z99, classification that represents a health condition due to an external cause. Though they are most applicable to injuries, they are also valid for use with such things as infections or diseases due to an external source, and other health conditions, such as a heart attack that occurs during strenuous physical activity.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.20.a.1
Additional codes with observation code (fragment)

observation code, but only if they are unrelated to the suspected condition being observed.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.21.c.6

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

Parent Code

Z79 Long term (current) drug therapy

More Specific Codes

Related Codes in Z79

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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