Z22.322 Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus is Z22.322 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
Z20-Z29: Persons with potential health hazards related to communicable diseases (Z20-Z29)
Category Z22
26 codes (20 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to Z22.322:

  • Colonization › MRSA (Methicillin resistant Staphylococcus aureus)
  • Carrier (suspected) of › staphylococci (Methicillin susceptible) › Methicillin resistant
  • Carrier (suspected) of › bacterial disease NEC › staphylococcal (Methicillin susceptible) › Methicillin resistant
  • Positive › culture (nonspecific) › nose › staphylococcus (Methicillin susceptible) › Methicillin resistant

Inclusion Terms

  • MRSA colonization

U.S. Hospital Utilization

  • An estimated 35,960 U.S. inpatient stays in 2023 included Z22.322 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

MSSA/MRSA colonization (Z22.321/Z22.322)

(c) Methicillin susceptible Staphylococcus aureus (MSSA) and MRSA colonization The condition or state of being colonized or carrying MSSA or MRSA is called colonization or carriage, while an individual person is described as being colonized or being a carrier. Colonization means that MSSA or MSRA is present on or in the body without necessarily causing illness. A positive MRSA colonization test might be documented by the provider as “MRSA screen positive” or “MRSA nasal swab positive”. Assign code Z22.322, Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus, for patients documented as having MRSA colonization. Assign code Z22.321, Carrier or suspected carrier of Methicillin susceptible Staphylococcus aureus, for patients documented as having MSSA colonization. Colonization is not necessarily indicative of a disease process or

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.1.e.1.c
MRSA colonization and infection—assign both colonization and infection

(d) MRSA colonization and infection If a patient is documented as having both MRSA colonization and infection during a hospital admission, code Z22.322, Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus, and a code for the MRSA infection may both be assigned.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.1.(d)

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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