T80.59 Anaphylactic reaction due to other serum

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Anaphylactic reaction due to other serum is T80.59 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
T80-T88: Complications of surgical and medical care, not elsewhere classified (T80-T88)
Category T80
53 codes (38 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to T80.59:

  • Reaction › serum › anaphylactic (immediate)
  • Shock › anaphylactic › serum
  • Allergy, allergic (reaction) (to) › serum › anaphylactic shock
  • Serum › allergy, allergic reaction › shock
  • Shock › anaphylactic › serum › specified NEC
  • Complication (s) (from) (of) › infusion (procedure) › serum reaction › anaphylactic shock
  • Allergy, allergic (reaction) (to) › shock (anaphylactic) › due to › serum NEC

Official Coding Guidelines

Complications of surgery and other medical care

G. Complications of surgery and other medical care When the admission is for treatment of a complication resulting from surgery or other medical care, the complication code is sequenced as the principal diagnosis. If the complication is classified to the T80-T88 series and the code lacks the necessary specificity in describing the complication, an additional code for the specific complication should be assigned.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section II.G
Sequence blood vessel/nerve injury first (fragment)

injury is to the blood vessels or nerves, that injury should be sequenced first.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.19.b.2

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

Parent Code

T80 Complications following infusion, transfusion and therapeutic injection

Related Codes in T80

T80 Complications following infusion, transfusion and therapeutic injection T80.0 Air embolism following infusion, transfusion and therapeutic injection T80.1 Vascular complications following infusion, transfusion and therapeutic injection T80.2 Infections following infusion, transfusion and therapeutic injection T80.21 Infection due to central venous catheter T80.211 Bloodstream infection due to central venous catheter T80.212 Local infection due to central venous catheter T80.218 Other infection due to central venous catheter T80.219 Unspecified infection due to central venous catheter T80.22 Acute infection following transfusion, infusion, or injection of blood and blood products T80.29 Infection following other infusion, transfusion and therapeutic injection T80.3 ABO incompatibility reaction due to transfusion of blood or blood products T80.30 ABO incompatibility reaction due to transfusion of blood or blood products, unspecified T80.31 ABO incompatibility with hemolytic transfusion reaction T80.310 ABO incompatibility with acute hemolytic transfusion reaction T80.311 ABO incompatibility with delayed hemolytic transfusion reaction T80.319 ABO incompatibility with hemolytic transfusion reaction, unspecified T80.39 Other ABO incompatibility reaction due to transfusion of blood or blood products T80.4 Rh incompatibility reaction due to transfusion of blood or blood products T80.40 Rh incompatibility reaction due to transfusion of blood or blood products, unspecified
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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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