Q96.4 Mosaicism, 45, X/other cell line(s) with abnormal sex chromosome

The ICD-10-CM code for Mosaicism, 45, X/other cell line(s) with abnormal sex chromosome is Q96.4 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

17: Congenital malformations, deformations and chromosomal abnormalities (Q00-QA0)

Section

Q90-Q99: Chromosomal abnormalities, not elsewhere classified (Q90-Q99)

Category Q96

8 codes (7 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to Q96.4:

• Mosaicism, mosaic (autosomal) (chromosomal) › 45,X/other cell lines NEC with abnormal sex chromosome

U.S. Hospital Utilization

• An estimated 70 U.S. inpatient stays in 2022 included Q96.4 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

POA indicator for congenital conditions/anomalies and Q00-Q99 exception

Congenital conditions and anomalies Assign “Y” for congenital conditions and anomalies except for categories Q00- Q99, Congenital anomalies, which are on the exempt list. Congenital conditions are always considered present on admission.

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)