O12.21 Gestational edema with proteinuria, first trimester

The ICD-10-CM code for Gestational edema with proteinuria, first trimester is O12.21 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

15: Pregnancy, childbirth and the puerperium (O00-O9A)

Section

O10-O16: Edema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium (O10-O16)

Category O12

22 codes (18 billable)

FY2026 Status

Stable since FY2024

U.S. Hospital Utilization

O12.21 appeared in too few sampled U.S. inpatient stays in 2021 to report a national estimate (AHRQ suppresses counts of 10 or fewer) — a rare inpatient diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)