M34.1 CR(E)ST syndrome

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for CR(E)ST syndrome is M34.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
M30-M36: Systemic connective tissue disorders (M30-M36)
Category M34
10 codes (8 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to M34.1:

  • CREST syndrome
  • CRST syndrome
  • Calcinosis (interstitial) (tumoral) (universalis) › with Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia (CREST syndrome)

Inclusion Terms

  • Combination of calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia

U.S. Hospital Utilization

  • An estimated 8,710 U.S. inpatient stays in 2023 included M34.1 among the documented diagnoses.
  • 195 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Osteoporosis without pathological fracture (M81)

Category M81, Osteoporosis without current pathological fracture, is for use for patients with osteoporosis who do not currently have a pathologic fracture due to the osteoporosis, even if they have had a fracture in the past. For patients with a history of osteoporosis fractures, status code Z87.310, Personal history of (healed) osteoporosis fracture, should follow the code from M81.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.13.d.1
Osteoporosis with current pathological fracture (M80)

Category M80, Osteoporosis with current pathological fracture, is for patients who have a current pathologic fracture at the time of an encounter. The codes under M80 identify the site of the fracture. A code from category M80, not a traumatic fracture code, should be used for any patient with known osteoporosis who suffers a fracture, even if the patient had a minor fall or trauma, if that fall or trauma would not usually break a normal, healthy bone.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.13.d.2

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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