M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]

✓ Billable ICD-10-CM 2026
Open M31.11 in Web App →

The ICD-10-CM code for Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA] is M31.11 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
M30-M36: Systemic connective tissue disorders (M30-M36)
Category M31
16 codes (13 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to M31.11:

  • HSCT-TMA (hematopoietic stem cell transplantation-associated thrombotic microangiopathy)
  • Microangiopathy (peripheral) › thrombotic › hematopoietic stem cell transplantation-associated [HSCT-TMA]
Code First
  • if applicable:
  • complications of bone marrow transplant (T86.0-)
  • complications of stem cell transplant (T86.5)
Use Additional Code
  • code to identify specific organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory distress syndrome (J80)
  • capillary leak syndrome (I78.8)
  • diffuse alveolar hemorrhage (R04.89)
  • encephalopathy (metabolic) (septic) (G93.41)
  • fluid overload, unspecified (E87.70)
  • graft versus host disease (D89.81-)
  • hemolytic uremic syndrome (D59.3-)
  • hepatic failure (K72.-)
  • hepatic veno-occlusive disease (K76.5)
  • idiopathic interstitial pneumonia (J84.11-)
  • sinusoidal obstruction syndrome (K76.5)

Inclusion Terms

  • Transplant-associated thrombotic microangiopathy [TA-TMA]

U.S. Hospital Utilization

  • An estimated 725 U.S. inpatient stays in 2023 included M31.11 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Osteoporosis without pathological fracture (M81)

Category M81, Osteoporosis without current pathological fracture, is for use for patients with osteoporosis who do not currently have a pathologic fracture due to the osteoporosis, even if they have had a fracture in the past. For patients with a history of osteoporosis fractures, status code Z87.310, Personal history of (healed) osteoporosis fracture, should follow the code from M81.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.13.d.1
Osteoporosis with current pathological fracture (M80)

Category M80, Osteoporosis with current pathological fracture, is for patients who have a current pathologic fracture at the time of an encounter. The codes under M80 identify the site of the fracture. A code from category M80, not a traumatic fracture code, should be used for any patient with known osteoporosis who suffers a fracture, even if the patient had a minor fall or trauma, if that fall or trauma would not usually break a normal, healthy bone.

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.13.d.2

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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