L27.0 Generalized skin eruption due to drugs and medicaments taken internally

The ICD-10-CM code for Generalized skin eruption due to drugs and medicaments taken internally is L27.0 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

12: Diseases of the skin and subcutaneous tissue (L00-L99)

Section

L20-L30: Dermatitis and eczema (L20-L30)

Category L27

6 codes (5 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to L27.0:

• Rash (toxic) › drug (internal use)
• Eruption › drug (generalized) (taken internally)
• Dermatitis (eczematous) › due to › vaccine or vaccination
• Dermatitis (eczematous) › due to › drugs and medicaments (generalized) (internal use)
• Eruption › skin (nonspecific) › due to inoculation/vaccination (generalized)

U.S. Hospital Utilization

• An estimated 39,910 U.S. inpatient stays in 2023 included L27.0 among the documented diagnoses.
• 3,845 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Pressure ulcer stages—L89 identifies site/stage; code all ulcers

a. Pressure ulcer stage codes 1) Pressure ulcer stages Codes in category L89, Pressure ulcer, identify the site and stage of the pressure ulcer. The ICD-10-CM classifies pressure ulcer stages based on severity, which is designated by stages 1-4, deep tissue pressure injury, unspecified stage, and unstageable. Assign as many codes from category L89 as needed to identify all the pressure ulcers the patient has, if applicable. See Section I.B.14. for pressure ulcer stage documentation by clinicians other than patient's provider.

Unstageable pressure ulcers—L89.--0 based on clinical documentation

2) Unstageable pressure ulcers Assignment of the code for unstageable pressure ulcer (L89.--0) should be based on the clinical documentation. These codes are used for

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)