F78.A1 SYNGAP1-related intellectual disability

The ICD-10-CM code for SYNGAP1-related intellectual disability is F78.A1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

5: Mental, Behavioral and Neurodevelopmental disorders (F01-F99)

Section

F70-F79: Intellectual Disabilities (F70-F79)

Category F78

4 codes (2 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to F78.A1:

• Disability, disabilities › intellectual › SYNGAP1-related
• Disability, disabilities › intellectual › genetic related › SYNGAP1-related
• Disability, disabilities › intellectual › with › pathogenic SYNGAP1 (genetic) (variant)
• Disability, disabilities › intellectual › genetic related › with › pathogenic SYNGAP1 (variant)

U.S. Hospital Utilization

F78.A1 appeared in too few sampled U.S. inpatient stays in 2023 to report a national estimate (AHRQ suppresses counts of 10 or fewer) — a rare inpatient diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Pain disorders related to psychological factors (TOC entry)

a. Pain disorders related to psychological factors ..................................................................... 43

Psychoactive substance use disorders (TOC entry)

b. Mental and behavioral disorders due to psychoactive substance use ................................... 43

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)