F48.1 Depersonalization-derealization syndrome

The ICD-10-CM code for Depersonalization-derealization syndrome is F48.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

5: Mental, Behavioral and Neurodevelopmental disorders (F01-F99)

Section

F40-F48: Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders (F40-F48)

Category F48

5 codes (4 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to F48.1:

• Derealization (neurotic)
• Depersonalization (in neurotic state) (neurotic) (syndrome)
• Disorder (of) › depersonalization
• Psychoneurosis, psychoneurotic › depersonalization
• Episode › depersonalization (in neurotic state)
• Neurosis, neurotic › depersonalization
• Syndrome › depersonalization (-derealization)
• Neurosis, neurotic › state › with depersonalization episode

U.S. Hospital Utilization

• An estimated 1,655 U.S. inpatient stays in 2023 included F48.1 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Pain disorders related to psychological factors (TOC entry)

a. Pain disorders related to psychological factors ..................................................................... 43

Psychoactive substance use disorders (TOC entry)

b. Mental and behavioral disorders due to psychoactive substance use ................................... 43

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)