F33.3 Major depressive disorder, recurrent, severe with psychotic symptoms
The ICD-10-CM code for Major depressive disorder, recurrent, severe with psychotic symptoms is F33.3 (FY2026). It is a billable, claim-ready diagnosis code.
Classification
- Section
- F30-F39: Mood [affective] disorders (F30-F39)
- Category F33
- 11 codes (9 billable)
- FY2026 Status
- Stable since FY2024
Also Known As
ICD-10-CM Alphabetic Index entries that lead to F33.3:
- Depression (acute) (mental) › endogenous (without psychotic symptoms) › with psychotic symptoms
- Depression (acute) (mental) › psychotic (single episode) › recurrent
- Depression (acute) (mental) › vital (recurrent) (without psychotic symptoms) › with psychotic symptoms
- Psychosis, psychotic › reactive (brief) (transient) (emotional stress) (psychological trauma) › depressive › recurrent
- Disorder (of) › depressive › major › recurrent › with psychotic features
- Disorder (of) › depressive › recurrent › current episode › severe (without psychotic symptoms) › with psychotic symptoms
Inclusion Terms
- Endogenous depression with psychotic symptoms
- Major depressive disorder, recurrent, with psychotic features
- Recurrent severe episodes of major depression with mood-congruent psychotic symptoms
- Recurrent severe episodes of major depression with mood-incongruent psychotic symptoms
- Recurrent severe episodes of major depression with psychotic symptoms
- Recurrent severe episodes of psychogenic depressive psychosis
- Recurrent severe episodes of psychotic depression
- Recurrent severe episodes of reactive depressive psychosis
U.S. Hospital Utilization
- An estimated 54,510 U.S. inpatient stays in 2023 included F33.3 among the documented diagnoses.
- 42,320 stays listed it as the principal diagnosis.
Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.
Official Coding Guidelines
Pain disorders related to psychological factors (TOC entry)a. Pain disorders related to psychological factors ..................................................................... 43
Psychoactive substance use disorders (TOC entry)b. Mental and behavioral disorders due to psychoactive substance use ................................... 43
Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026