F16.221 Hallucinogen dependence with intoxication with delirium
The ICD-10-CM code for Hallucinogen dependence with intoxication with delirium is F16.221 (FY2026). It is a billable, claim-ready diagnosis code.
Classification
- Section
- F10-F19: Mental and behavioral disorders due to psychoactive substance use (F10-F19)
- Category F16
- 53 codes (40 billable)
- FY2026 Status
- Stable since FY2024
Also Known As
ICD-10-CM Alphabetic Index entries that lead to F16.221:
- Disorder (of) › hallucinogen use › moderate or severe › with › hallucinogen intoxication delirium
- Delirium, delirious (acute or subacute) (not alcohol- or drug-induced) › due to (secondary to) › hallucinogen intoxication › in › dependence
- Disorder (of) › phencyclidine use › moderate or severe › with › phencyclidine intoxication delirium
- Delirium, delirious (acute or subacute) (not alcohol- or drug-induced) › due to (secondary to) › phencyclidine intoxication (acute) › in › dependence
- Dependence (on) (syndrome) › drug NEC › hallucinogen › with › intoxication › with delirium
U.S. Hospital Utilization
F16.221 appeared in too few sampled U.S. inpatient stays in 2023 to report a national estimate (AHRQ suppresses counts of 10 or fewer) — a rare inpatient diagnosis.
Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.
Official Coding Guidelines
Pain disorders related to psychological factors (TOC entry)a. Pain disorders related to psychological factors ..................................................................... 43
Psychoactive substance use disorders (TOC entry)b. Mental and behavioral disorders due to psychoactive substance use ................................... 43
Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026