F15.221 Other stimulant dependence with intoxication delirium

✓ Billable ICD-10-CM 2026
Open F15.221 in Web App →

The ICD-10-CM code for Other stimulant dependence with intoxication delirium is F15.221 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
F10-F19: Mental and behavioral disorders due to psychoactive substance use (F10-F19)
Category F15
61 codes (48 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to F15.221:

  • Delirium, delirious (acute or subacute) (not alcohol- or drug-induced) › due to (secondary to) › amphetamine intoxication › in › dependence
  • Disorder (of) › amphetamine (or other stimulant) use › moderate or severe › with › intoxication delirium
  • Dependence (on) (syndrome) › drug NEC › stimulant NEC › with › intoxication › with › delirium

U.S. Hospital Utilization

  • An estimated 340 U.S. inpatient stays in 2023 included F15.221 among the documented diagnoses.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Pain disorders related to psychological factors (TOC entry)

a. Pain disorders related to psychological factors ..................................................................... 43

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.5.a
Psychoactive substance use disorders (TOC entry)

b. Mental and behavioral disorders due to psychoactive substance use ................................... 43

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.5.b

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

Parent Code

F15 Other stimulant related disorders

Related Codes in F15

F15 Other stimulant related disorders F15.1 Other stimulant abuse F15.10 Other stimulant abuse, uncomplicated F15.11 Other stimulant abuse, in remission F15.12 Other stimulant abuse with intoxication F15.120 Other stimulant abuse with intoxication, uncomplicated F15.121 Other stimulant abuse with intoxication delirium F15.122 Other stimulant abuse with intoxication with perceptual disturbance F15.129 Other stimulant abuse with intoxication, unspecified F15.13 Other stimulant abuse with withdrawal F15.14 Other stimulant abuse with stimulant-induced mood disorder F15.15 Other stimulant abuse with stimulant-induced psychotic disorder F15.150 Other stimulant abuse with stimulant-induced psychotic disorder with delusions F15.151 Other stimulant abuse with stimulant-induced psychotic disorder with hallucinations F15.159 Other stimulant abuse with stimulant-induced psychotic disorder, unspecified F15.18 Other stimulant abuse with other stimulant-induced disorder F15.180 Other stimulant abuse with stimulant-induced anxiety disorder F15.181 Other stimulant abuse with stimulant-induced sexual dysfunction F15.182 Other stimulant abuse with stimulant-induced sleep disorder F15.188 Other stimulant abuse with other stimulant-induced disorder
Search all 70,000+ ICD-10-CM codes →
Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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