F11.29 Opioid dependence with unspecified opioid-induced disorder

The ICD-10-CM code for Opioid dependence with unspecified opioid-induced disorder is F11.29 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

5: Mental, Behavioral and Neurodevelopmental disorders (F01-F99)

Section

F10-F19: Mental and behavioral disorders due to psychoactive substance use (F10-F19)

Category F11

58 codes (45 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to F11.29:

• Dependence (on) (syndrome) › drug NEC › opioid › with › unspecified disorder

U.S. Hospital Utilization

• An estimated 1,510 U.S. inpatient stays in 2023 included F11.29 among the documented diagnoses.
• 70 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Assign O99.32 + secondary F11-F16/F18-F19 for drug use

3) Drug use during pregnancy, childbirth and the puerperium Codes under subcategory O99.32, Drug use complicating pregnancy, childbirth, and the puerperium, should be assigned for any pregnancy case when a patient uses drugs during the pregnancy or postpartum. This can involve illegal drugs, or inappropriate use or abuse of prescription drugs. Secondary code(s) from categories F11-F16 and F18-F19 should also be assigned to identify manifestations of the drug use.

Pain disorders related to psychological factors (TOC entry)

a. Pain disorders related to psychological factors ..................................................................... 43

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)