E27.1 Primary adrenocortical insufficiency

The ICD-10-CM code for Primary adrenocortical insufficiency is E27.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

4: Endocrine, nutritional and metabolic diseases (E00-E89)

Section

E20-E35: Disorders of other endocrine glands (E20-E35)

Category E27

11 codes (9 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to E27.1:

• Addison's › disease (bronze) or syndrome
• Melanosis › adrenal
• Hypoadrenocorticism › primary
• Hypoadrenalism, hypoadrenia › primary
• Adrenalitis, adrenitis › autoimmune
• Melanosis › suprarenal
• Disease, diseased › bronze Addison's
• Melanosis › addisonian

Inclusion Terms

• Addison's disease
• Autoimmune adrenalitis

U.S. Hospital Utilization

• An estimated 28,195 U.S. inpatient stays in 2023 included E27.1 among the documented diagnoses.
• 1,375 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Diabetes mellitus (TOC entry)

a. Diabetes mellitus ................................................................................................................... 39

Obesity (TOC entry)

b. Obesity .................................................................................................................................. 42

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)