E25.0 Congenital adrenogenital disorders associated with enzyme deficiency

The ICD-10-CM code for Congenital adrenogenital disorders associated with enzyme deficiency is E25.0 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

4: Endocrine, nutritional and metabolic diseases (E00-E89)

Section

E20-E35: Disorders of other endocrine glands (E20-E35)

Category E25

4 codes (3 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to E25.0:

• Adrenogenitalism, congenital
• Adrenogenital syndrome › congenital
• Defect, defective › 3-beta-hydroxysteroid dehydrogenase
• Deficiency, deficient › 11-hydroxylase
• Defect, defective › 11-hydroxylase
• Deficiency, deficient › 21-hydroxylase
• Defect, defective › 21-hydroxylase
• Adrenogenital syndrome › salt loss

Inclusion Terms

• Congenital adrenal hyperplasia
• 21-Hydroxylase deficiency
• Salt-losing congenital adrenal hyperplasia

U.S. Hospital Utilization

• An estimated 2,215 U.S. inpatient stays in 2023 included E25.0 among the documented diagnoses.
• 145 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Diabetes mellitus (TOC entry)

a. Diabetes mellitus ................................................................................................................... 39

Obesity (TOC entry)

b. Obesity .................................................................................................................................. 42

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)