E05.21 Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
The ICD-10-CM code for Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm is E05.21 (FY2026). It is a billable, claim-ready diagnosis code.
Classification
- Section
- E00-E07: Disorders of thyroid gland (E00-E07)
- Category E05
- 22 codes (14 billable)
- FY2026 Status
- Stable since FY2024
Also Known As
ICD-10-CM Alphabetic Index entries that lead to E05.21:
- Plummer's disease › with thyroid storm
- Nodule (s), nodular › thyroid (cold) (gland) (nontoxic) › toxic or with hyperthyroidism › with thyroid storm
- Goiter (plunging) (substernal) › nodular (nontoxic) (due to) › toxic › with thyroid storm
- Struma › nodosa (simplex) › toxic or with hyperthyroidism › with thyroid storm
- Nodule (s), nodular › thyroid (cold) (gland) (nontoxic) › with thyrotoxicosis › with thyroid storm
- Goiter (plunging) (substernal) › multinodular (cystic) (nontoxic) › toxic or with hyperthyroidism › with thyroid storm
- Struma › nodosa (simplex) › toxicosa › with thyroid storm
- Goiter (plunging) (substernal) › nodular (nontoxic) (due to) › with › hyperthyroidism › with thyroid storm
U.S. Hospital Utilization
- An estimated 165 U.S. inpatient stays in 2023 included E05.21 among the documented diagnoses.
- 100 stays listed it as the principal diagnosis.
Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.
Official Coding Guidelines
Diabetes mellitus (TOC entry)a. Diabetes mellitus ................................................................................................................... 39
Obesity (TOC entry)b. Obesity .................................................................................................................................. 42
Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026