D76.3 Other histiocytosis syndromes

The ICD-10-CM code for Other histiocytosis syndromes is D76.3 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Section

D70-D77: Other disorders of blood and blood-forming organs (D70-D77)

Category D76

4 codes (3 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to D76.3:

• Histiocytosis
• Xanthogranuloma
• Reticulohistiocytoma (giant-cell)
• Granuloma › reticulohistiocytic
• Histiocytosis › polyostotic sclerosing
• Histiocytosis › lipid, lipoid
• Histiocytosis › sinus, with massive lymphadenopathy
• Histiocytosis › non-Langerhans cell

Inclusion Terms

• Reticulohistiocytoma (giant-cell)
• Sinus histiocytosis with massive lymphadenopathy
• Xanthogranuloma

U.S. Hospital Utilization

• An estimated 1,150 U.S. inpatient stays in 2023 included D76.3 among the documented diagnoses.
• 80 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)