D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Vitamin B12 deficiency anemia due to intrinsic factor deficiency is D51.0 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
D50-D53: Nutritional anemias (D50-D53)
Category D51
7 codes (6 billable)
FY2026 Status
Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to D51.0:

  • Lichtheim's disease or syndrome
  • Biermer's (pernicious) anemia or disease
  • Runeberg's disease
  • Addison-Biermer anemia (pernicious)
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › combined system disease NEC
  • Addison's › anemia (pernicious)
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › Addison (-Biermer) (pernicious)
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › Biermer's (pernicious)

Inclusion Terms

  • Addison anemia
  • Biermer anemia
  • Pernicious (congenital) anemia
  • Congenital intrinsic factor deficiency

U.S. Hospital Utilization

  • An estimated 12,420 U.S. inpatient stays in 2023 included D51.0 among the documented diagnoses.
  • 345 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Chapter 3 TOC entry

3. Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) ............................................................................................. 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3
Reserved for future guideline expansion

Reserved for future guideline expansion ...................................................................................... 39

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.3.Reserved

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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