D48.1 Neoplasm of uncertain behavior of connective and other soft tissue

The ICD-10-CM code for Neoplasm of uncertain behavior of connective and other soft tissue is D48.1 (FY2026). It is a non-billable category code — select a more specific code below for claims.

Classification

Chapter

2: Neoplasms (C00-D49)

Section

D37-D48: Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

Category D48

25 codes (21 billable)

FY2026 Status

Stable since FY2024

Inclusion Terms

• Neoplasm of uncertain behavior of connective tissue of ear
• Neoplasm of uncertain behavior of connective tissue of eyelid
• Stromal tumors of uncertain behavior of digestive system

U.S. Hospital Utilization

• An estimated 1,585 U.S. inpatient stays in 2023 included D48.1 among the documented diagnoses.
• 495 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Tx of primary site (TOC entry)

a. Admission/Encounter for treatment of primary site ............................................................. 33

Tx of secondary site (TOC entry)

b. Admission/Encounter for treatment of secondary site .......................................................... 33

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)