C83.390 Primary central nervous system lymphoma

✓ Billable ICD-10-CM 2026
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The ICD-10-CM code for Primary central nervous system lymphoma is C83.390 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Section
C81-C96: Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
Category C83
87 codes (78 billable)
FY2026 Status
Introduced in FY2025

Also Known As

ICD-10-CM Alphabetic Index entries that lead to C83.390:

  • Lymphoma (of) (malignant) › primary central nervous system (brain) (meninges) (PCNSL) (spinal cord)
  • Lymphoma (of) (malignant) › diffuse large cell › primary central nervous system (brain) (meninges) (PCNSL) (spinal cord)
  • Lymphoma (of) (malignant) › primary central nervous system (brain) (meninges) (PCNSL) (spinal cord) › diffuse large B-cell
Excludes1
Not coded here. These conditions should NOT be coded together with C83.390.
  • Primary central nervous system lymphoma, Burkitt (C83.79)
  • Primary central nervous system lymphoma, lymphoblastic (C83.59)
  • Primary central nervous system lymphoma, other (C83.89)
  • Primary central nervous system lymphoma, peripheral T-cell (C84.49)

Inclusion Terms

  • PCNSL of brain
  • PCNSL of meninges
  • PCNSL of spinal cord
  • PCNSL NOS

Official Coding Guidelines

Tx of primary site (TOC entry)

a. Admission/Encounter for treatment of primary site ............................................................. 33

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.2.a
Tx of secondary site (TOC entry)

b. Admission/Encounter for treatment of secondary site .......................................................... 33

— ICD-10-CM Official Guidelines for Coding and Reporting, FY2026, Section I.C.2.b

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

Related Codes

Parent Code

C83 Non-follicular lymphoma

Related Codes in C83

C83 Non-follicular lymphoma C83.0 Small cell B-cell lymphoma C83.00 Small cell B-cell lymphoma, unspecified site C83.01 Small cell B-cell lymphoma, lymph nodes of head, face, and neck C83.02 Small cell B-cell lymphoma, intrathoracic lymph nodes C83.03 Small cell B-cell lymphoma, intra-abdominal lymph nodes C83.04 Small cell B-cell lymphoma, lymph nodes of axilla and upper limb C83.05 Small cell B-cell lymphoma, lymph nodes of inguinal region and lower limb C83.06 Small cell B-cell lymphoma, intrapelvic lymph nodes C83.07 Small cell B-cell lymphoma, spleen C83.08 Small cell B-cell lymphoma, lymph nodes of multiple sites C83.09 Small cell B-cell lymphoma, extranodal and solid organ sites C83.0A Small cell B-cell lymphoma, in remission C83.1 Mantle cell lymphoma C83.10 Mantle cell lymphoma, unspecified site C83.11 Mantle cell lymphoma, lymph nodes of head, face, and neck C83.12 Mantle cell lymphoma, intrathoracic lymph nodes C83.13 Mantle cell lymphoma, intra-abdominal lymph nodes C83.14 Mantle cell lymphoma, lymph nodes of axilla and upper limb C83.15 Mantle cell lymphoma, lymph nodes of inguinal region and lower limb
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Reviewed by Prajwal Shrestha, CPC, CRC
Certified Professional Coder (CPC) and Certified Risk Adjustment Coder (CRC) · AAPC Member ID 01997614 · About · Editorial policy · Content last reviewed: 2025-10-01

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