B45.1 Cerebral cryptococcosis

The ICD-10-CM code for Cerebral cryptococcosis is B45.1 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

1: Certain infectious and parasitic diseases (A00-B99)

Section

B35-B49: Mycoses (B35-B49)

Category B45

8 codes (7 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to B45.1:

• Cryptococcosis, cryptococcus (infection) (neoformans) › meningitis
• Encephalitis (chronic) (hemorrhagic) (idiopathic) (nonepidemic) (spurious) (subacute) › Torula, torular (cryptococcal)
• Cryptococcosis, cryptococcus (infection) (neoformans) › meningocerebralis
• Meningitis (basal) (basic) (brain) (cerebral) (cervical) (congestive) (diffuse) (hemorrhagic) (infantile) (membranous) (metastatic) (nonspecific) (pontine) (progressive) (simple) (spinal) (subacute) (sympathetic) (toxic) › Torula histolytica (cryptococcal)
• Meningitis (basal) (basic) (brain) (cerebral) (cervical) (congestive) (diffuse) (hemorrhagic) (infantile) (membranous) (metastatic) (nonspecific) (pontine) (progressive) (simple) (spinal) (subacute) (sympathetic) (toxic) › cryptococcal
• Cryptococcosis, cryptococcus (infection) (neoformans) › cerebral
• Meningomyelitis › cryptococcal
• Meningoencephalomyelitis › due to › Torula

Inclusion Terms

• Cryptococcal meningitis
• Cryptococcosis meningocerebralis

U.S. Hospital Utilization

• An estimated 2,185 U.S. inpatient stays in 2023 included B45.1 among the documented diagnoses.
• 710 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

HIV Infections (TOC entry)

a. Human Immunodeficiency Virus (HIV) Infections .............................................................. 19

Infectious agents causing diseases in other chapters (TOC)

b. Infectious agents as the cause of diseases classified to other chapters ................................. 22

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)