A49.01 Methicillin susceptible Staphylococcus aureus infection, unspecified site

The ICD-10-CM code for Methicillin susceptible Staphylococcus aureus infection, unspecified site is A49.01 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

1: Certain infectious and parasitic diseases (A00-B99)

Section

A30-A49: Other bacterial diseases (A30-A49)

Category A49

9 codes (7 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to A49.01:

• MSSA (Methicillin susceptible Staphylococcus aureus) › infection
• Infection, infected, infective (opportunistic) › methicillin › susceptible Staphylococcus aureus (MSSA)
• Infection, infected, infective (opportunistic) › staphylococcal, unspecified site › aureus (methicillin susceptible) (MSSA)

Inclusion Terms

• Methicillin susceptible Staphylococcus aureus (MSSA) infection
• Staphylococcus aureus infection NOS

U.S. Hospital Utilization

• An estimated 4,590 U.S. inpatient stays in 2023 included A49.01 among the documented diagnoses.
• 130 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

HIV Infections (TOC entry)

a. Human Immunodeficiency Virus (HIV) Infections .............................................................. 19

Infectious agents causing diseases in other chapters (TOC)

b. Infectious agents as the cause of diseases classified to other chapters ................................. 22

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)