A41.02 Sepsis due to Methicillin resistant Staphylococcus aureus

The ICD-10-CM code for Sepsis due to Methicillin resistant Staphylococcus aureus is A41.02 (FY2026). It is a billable, claim-ready diagnosis code.

Classification

Chapter

1: Certain infectious and parasitic diseases (A00-B99)

Section

A30-A49: Other bacterial diseases (A30-A49)

Category A41

19 codes (15 billable)

FY2026 Status

Stable since FY2024

Also Known As

ICD-10-CM Alphabetic Index entries that lead to A41.02:

• Sepsis (generalized) (unspecified organism) › MRSA (Methicillin resistant Staphylococcus aureus)
• MRSA (Methicillin resistant Staphylococcus aureus) › sepsis
• Sepsis (generalized) (unspecified organism) › Staphylococcus, staphylococcal › aureus (methicillin susceptible) (MSSA) › methicillin resistant (MRSA)

U.S. Hospital Utilization

• An estimated 68,755 U.S. inpatient stays in 2023 included A41.02 among the documented diagnoses.
• 47,010 stays listed it as the principal diagnosis.

Source: National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, 2016–2023. National survey-weighted estimates.

Official Coding Guidelines

Combination codes for MRSA infection

(a) Combination codes for MRSA infection When a patient is diagnosed with an infection that is due to methicillin resistant Staphylococcus aureus (MRSA), and that infection has a combination code that includes the causal organism (e.g., sepsis, pneumonia) assign the appropriate combination code for the condition (e.g., code A41.02, Sepsis due to Methicillin resistant Staphylococcus aureus or code J15.212, Pneumonia due to Methicillin resistant Staphylococcus aureus). Do not assign code B95.62, Methicillin resistant Staphylococcus aureus infection as the cause of diseases classified elsewhere, as an additional code, because the combination code includes the type of infection and the MRSA organism. Do not assign a code from subcategory Z16.11, Resistance to penicillins, as an additional diagnosis. See Section C.1. for instructions on coding and sequencing of sepsis and severe sepsis.

HIV Infections (TOC entry)

a. Human Immunodeficiency Virus (HIV) Infections .............................................................. 19

Source: CMS — ICD-10-CM Official Guidelines for Coding and Reporting, FY2026

References

• CMS — ICD-10-CM Official Code Set and Guidelines, FY2026
• CDC/NCHS — ICD-10-CM Files and Browser Tool
• AHRQ — HCUP National Inpatient Sample, Frequencies by Diagnosis Code (2016–2023)